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For the candesartan ester with benzene sulfonic acid amlodipine piece what is the difference? Candesartan ester manufacturers to introduce the following:

Main ingredients are amlodipine reasons. Difference is only different substituents, a benzene ring is replaced the sulfonic group one hydrogen atom; Another is the methyl sulfonic group was replaced hydrogen atoms.

Is larger than the molecular weight of methyl of benzene ring, the space steric hindrance is bigger, the speed of drug release more slowly, last longer time. Is more suitable for high blood pressure, the chronic diseases of smooth, continuous and slow way of drug delivery.

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